Venom made his first appearance in The Amazing Spider-Man #299 (Dec. 1984). Venom is the name of several characters (hosts) throughout the Marvel Universe.
The first Venom was Eddie Brock, a reporter for the Daily Globe before it comes to light that he has fabricated a story revealing the identity of the Sin-Eater. Shortly after the story was published, Spider-Man catches the real Sin-Eater, disgracing Brock as a news reporter and costing him his job and then his wife. Now writing for cheap gossip magazines, Brock centers his frustration on utter loathing of Spider-Man, which only escalates when it is revealed that Brock has cancer. In response to this news, Brock begins working out, bringing his body to levels of amazing athletic performance. Still unable to cope with his misfortune, Brock contemplates suicide and goes to a church to pray for forgiveness. Meanwhile, the Symbiote, having recovered and needing another human host in order to survive, finds itself psychically attracted to Brock for both his increased adrenaline and mutual hatred for Spider-Man.
In The Amazing Spider-Man #298, they formed into the first version of the dark, villainous creature known as Venom. Venom first appeared at the end of issue #299, which led into the first Venom story in issue #300. The name Venom originally applied to Brock, rather than the Symbiote—which Brock refers to as his "Other". Over the years, as the Symbiote gained more intelligence and moved to additional human hosts, the name began to apply to the Symbiote as well as its hosts. As Venom, Brock fights Spider-Man many times, winning on several occasions. Venom repeatedly tries to kill Peter Parker/Spider-Man—both when the latter was in and out of costume. Thus Parker is forced to abandon his "black costume," which the Symbiote had been mimicking, after Venom confronts Parker's wife Mary Jane.
Venom escapes from the supervillain prison, The Vault, to torment Spider-Man and his family. The Symbiote is finally rendered comatose after being subdued by Styx's plague virus, and Eddie Brock is subsequently placed in Ryker's Island Prison. When the Symbiote recovers and returns to free Brock, it leaves a spawn to bond with Brock's psychotic serial-killer cellmate Cletus Kasady, who becomes Carnage. Meanwhile, Venom and Spider-Man fight on a deserted island, and Spider-Man strands Venom there after faking his own death. Soon after, however, Spider-Man brings Venom back to New York in order to stop Carnage's killing spree. After being incarcerated once again, Venom is used to create five new Symbiotes, which are all paired with human hosts.
As well as helping Eddie Brock to seek continued revenge against Spider-Man, the Symbiote also aids Brock in a sporadic career as a vigilante. He and the Symbiote occasionally share a desire to protect innocent people from harm, even if it means working side-by-side with the hated Spider-Man. This is especially true when Venom combats the entity he believes to be his spawn, Carnage. When Spider-Man helps Venom save Brock's ex-wife Ann Weying, the two form a temporary truce, though this falls apart after Weying's suicide.
The symbiote is temporarily stolen by U.S. Senator Steward Ward, who hopes to better understand his own alien infection by researching the symbiote before it returns to Brock. Now, however, it dominates its host, Brock, rather than vice versa. Eventually, Eddie Brock and the Symbiote go their separate ways as the Symbiote grows tired of having a diseased host and Eddie rejects its growing bloodlust, leading him to sell the Symbiote at a super villain auction.
The Venom Symbiote approached Mac Gargan and offered him new abilities as the second Venom. Gargan bonded with the creature, which would later give him an extra edge as part of Norman Osborn's Sinister Twelve. As the Avengers dealt with the rest of the Twelve, Spider-Man swiftly defeated Gargan, even with these additional powers, which Spider-Man suggests is attributed to the fact that Mac Gargan does not hate Spider-Man as much as Eddie Brock did. Gargan later became a member of a sub-group of the Thunderbolts, which was drafted by the Avengers to hunt down the members of the fugitive New Avengers. It was then revealed that he had been outfitted with electrical implants by the government to keep the Symbiote in check. When in the Venom persona, Gargan retained very little of his original personality and was controlled almost completely by the Symbiote, which drove him to cannibalism. When the Symbiote was dormant in his body, he expressed nausea and fear of the organism. During a fight with "Anti-Venom" (Eddie Brock), he and his Symbiote were separated, and the Venom Symbiote was nearly destroyed. Blobs of it still existed in his bloodstream, however, so Osborn injected Gargan with a vaccine for Anti-Venom's healing powers, which restored the Symbiote by causing the remaining pieces of it to expand rapidly. Gargan dons a Scorpion battle armor over the Symbiote while it heals, causing him to become what Spider-Man calls "Ven-orpion" although when the Symbiote is fully restored it shatters the armor.
After ingesting a chemical given to him by Norman Osborn, Venom transforms into a more human appearance similar to the Black-Suited Spider-Man. Osborn introduces him as The Amazing Spider-Man, a member of the Dark Avengers, while unveiling the team. After the Siege of Asgard, Gargan and most of the Dark Avengers were taken into custody. While being held on the Raft, the Venom Symbiote was forcefully removed from him, ending his career as Venom.
On December 9, 2010, Marvel Comics announced a new "black ops" Venom owned by the government. The new Venom will be featured in a new series called Venom in March 2011. The birth of the new Venom can be seen in The Amazing Spider-Man #654.1 in February 2011. On January 28, 2011, the identity of "black ops" Venom was revealed to be Flash Thompson. Flash is hired by the government to be a special agent wearing the Venom symbiote. Flash is only allowed to wear the suit for up to 48 hours, or risk a permanent bonding with the symbiote. The Government is also equipped with a "kill switch" designed to take Flash out if he loses control. Along with the alien, Flash is equipped with a "Multi-Gun" designed to change into any type of gun Flash needs. Flash has battled Jack-o-Lantern, fought to stop Anti-Vibranium, and fought Kraven the Hunter in the Savage Land. dadadadad