Jeremy Irons is a great actor but he's just too evil for Alfred. I'm sorry but I hated Zombieland and The Social Network. Jessie Eisenberg is a bad actor as well. He's also way too young.
For Lex Luthor:
Known for: Tombstone (1993), Demon Knight (1995) and Zoolander (2001).
Reason: Well he looks the animated series version. After watching Demon Knight he can play a charismatic figure but in the shadows some who is cold and maniacal/terrifying figure. Not to mention his voice sounds like Clancy Brown.
Known for: Kick Ass (2010), Green Lantern (2011), and Zero Dark Thirty (2013).
Reason: I know he was Sinestro, but I don't care. After watching Kick Ass he would nail this role.
Known for: Superman II (1980), Star Wars Episode I: The Phantom Menace/Bowfinger/The Limey (1999) and The Adjustment Bureau (2010).
Reason: I know he was Zod in Superman II. Chris Evans was Human Torch and Captain America so why not? He's a great/underrated British actor who can be warm/kind and at the same time he can also be a bad ass. I think he would do an amazing job. KNEEL BEFORE ALFRED!!!!!!! LOL.
Known for: Ms.Doubtfire (1993), Goldeneye (1995), and Mars Attacks (1996).
Reasons: A nice James Bond nod. Go ahead hate me. He's my favorite James Bond. If you could believe Alfred was a spy when he was younger.
If you disagree please be respectful. Let me know in the comments.
Ps. Bryan Cranston should be Gordon.