LEONARDO DICAPRIO AS GREEN GOBLIN
He is a great actor who always shocks us in every film he is in, but why him as Goblin - because of his performance in Shutter Island. From that day on we learned that DiCaprio could play a mentally ill crazy character.
MARK WAHLBERG AS THE SCORPION
Mark Wahlberg always plays good thug characters and even better characters out for revenge. Mark would be perfect for this role as he is the same size and he has the same attitude.
JEREMY IRONS AS MYSTERIO
Do I really have to explain why?
ZACH EFFRON AS MOLTEN MAN
Now this one may be a little crazy but the guy usually plays weird roles and I think this would be a perfect role for him. And if both of them have anything in common is that they love to take a bet.
PAUL GIAMATTI AS THE RHINO
I would not change the casting - Paul Giamatti is a perfect choice for the Rhino. The Rhino is suppose to be an idiot and Paul makes it work.
AND FINALLY DRUM ROLL PLEASE.................................
ANDREW GARFIELD AS SPIDER-MAN
Now I know your saying whaaaaaaaat?! But this has happened, my sinister six would go along the lines of the ultimate six were goblin recruits spidey as apart of the team but spidey declines, and as for the casting keep it the same in my opinion. Andrew is the best Spider-Man on the big screen so far.