Centered around drug dealing suburban mother Nancy Botwin, Weeds is a must see for the comedic drama seeker. Showtime's prized jewel is riddled with crazy plots, relate-able characters, and hilarious jokes.
Grey's Anatomy (2005-)
This beloved medical drama centers on surgical intern Meredith Grey and the staff of the Seattle Grace Mercy West Hospital she works in. This long going drama has enticed millions with its emotion drawing action and its ability to redefine its characters each season.
Sons of Anarchy (2008-)
This deliciously nitty-gritty drama centers on new father Jax Teller and his dangerously addicting motorcycle club the Sons of Anarchy. Tears will fall, blood will run, and your breath will be stolen in this FX classic. With the last season slated to premiere on FX soon, the show is a must see.
JJ Abram's hit show is an absolute gem that appeals to every genre of television. Fringe focuses on FBI Agent Olivia Dunham who works for the Fringe Division of the FBI. The sole purpose of the Fringe Division is to solve cases involved in supernatural phenomena. Buckle up and get ready for parallel universes with clones, ghosts, flesh melting contagions, and a mad scientist who loves to take drugs.
Doctor Who (2005-)
Doctor Who is a much loved British sci-fi show that centers around an alien named The Doctor. In this 2005 return from a 1989 (not including the TV movie) hiatus, The Doctor travels through time and space with his companion Rose causing and fixing problems. Doctor Who just celebrated it's 50 years anniversary but the great thing is: you can start with the 1st (2005) season and not be lost. Also, check out Doctor Who's spin off show Torchwood. Check into this fandom and enjoy your stay!
Note: This is not in any particular order
Honorable Mentions: Game of Thrones, Homeland, Justice League, Breaking Bad, and Supernatural.