If Kevin Smith's hint/rumor is true, then we could see a Spider-Woman solo movie. Fans are going crazy with this! I think this is great! Spider-Woman needs to be known. To readers who know nothing about her see the facts below. Her name is Jessica Drew. She has S.H.I.E.L.D., HYDRA and Avengers ties so Marvel Studios has the rights to her. She is in no way related to Peter Parker. Powers and abilities: Flight, pheromones(attract guys to her. Basically charm speak), bio-electric venom blasts (energy projectiles), hand-to-hand combat training do.
Origin: She was little when she suffered uranium poisoning. Her father, Johnathan Drew, injected her with an experimental spider-serum and sealed her in a genetic accelerator in 1931. While in stasis, decades went by her aging was slowed drastically. She awoke with amnesia, and HYDRA found her and had called her Arachne and set her against S.H.I.E.L.D., she was later reformed by Nick Fury and turned against HYDRA as double agent for S.H.I.E.L.D.
How to fit her in the Marvel Cinematic Universe: keep her same origin story. Or they can make her a HYDRA experiment gone wrong if they want to be fresh like they are for Star-Lord's father.
Alisha Grauso, a fellow contributor, made an article about potential actresses. I recommend you check it out, great choices!