I know some people want them completely separate and others want a massive crossover. I want a massive crossover. I love it when teams come together. I love joint ops stuff! I was on Comicbook.com earlier and found a page about Thanos, needless to say, I was intrigued.
Thanos Imperative could be the potential Guardians 2 story line. This one, the Guardians have align with Thanos and are then betrayed. Star-Lord and Nova stay behind to keep him contained and are presumed dead. Nova obviously won't be in it so he'll be replaced. That's just the gist of it. I really hope we see the Guardians help the Avengers at some point. They need all the help they can get when they are fighting him.