Serinda Swan herself is a great actress. She has exceeded in almost all of her roles on the big screen and is always keen for a role.The 'She-Hulk' Character (Jennifer Walters), Has some similarities between the actress and the fictional character, Well, Not all hence the green skin. She shrikes a Resemblance with the fictional character's characteristics such as, Serinda having the athletic look we expect to see in She-Hulk, Her being the same height as Jennifer in the comics, Both being 5'7, and has almost the perfect representation of the characters face from the original Marvel Comic.
This isn't the first for Serinda playing a Superhero or Supervillan. She fluently played Zatanna Zatara in Smallville and portrayed the look and feel of the character well during 2009 to 2010.
In conclusion, personally I think she will fit the role perfectly. From what I've said She could possibly portray the Fiction Marvel Character's way's of how they operated in her Comic book adaptation.