Sometimes stars have so much chemistry on screen, it's hard to believe they're only acting. These 26 actors met on set and stayed best friends forever!
13. Cara Delevingne & Nat Wolff
They might have started out playing crushes in Paper Towns, but in real life these two are still great friends!
12. Vanessa Hudgens & Ashley Tisdale
These two Disney darlings may have played enemies in High School Musical, but in real life they're as close as can be.
11. Snooki & JWoww
These two party girls used to live the wild life on Jersey Shore. Now they're both moms, and it looks like their kids are just as good friends as they are!
10. Chace Crawford & Ed Westwick
As if they're on-screen bromance in Gossip Girl could get any cuter, these two are actually bros in real life.
9. Lea Michele & Chris Colfer
8. BJ Novak & Mindy Kaling
These two met as writers on The Office and dated for a while. Even though they're not a couple anymore, they're proof that exes can still be friends.
7. Ben Affleck & Matt Damon
These two best buds wrote and won an Oscar for Good Will Hunting, and they're always there to support each other in real life.
6. Brad Pitt & George Clooney
These two super stars started bro-ing out on the set of Ocean's Eleven, and they've carried on an infamous prank war ever since. Listen to Clooney's story about one of the crazy pranks the interview below.
5. Michelle Williams & Busy Philips
Busy Philips played newcomer Audrey on Dawson's Creek, but she and Williams hit it off from the start. They vacation together and Williams even took Philips as her date to the Oscars!
4. Donald Faison & Zach Braff
No one is better friends than Turk and JD from Scrubs... except Donald and Zach.
3. Kate Winslet & Leonardo DiCaprio
This one's a friendship for the ages. And it really is just that — platonic. Kate and Leo have been buddies since she convinced him to do Titanic, and 20 years later we still can't get enough of these two.
2. Courtney Cox & Jen Aniston
Monica and Rachel might not live together anymore, but Jen and Courtney will always be super close. Courtney was Jen's maid of honor at her wedding to Justin Theroux, and Jen is godmother to Courtney's daughter, Coco.
1. Tina Fey & Amy Poehler
The two funniest ladies in show business met at Chicago's Improv Olympic, and have gone on to make movies together (Mean Girls, Sisters), be feminist champions, and make everyone love them as much as they love each other.