As we all know, Marvel has entertained a lot of people. Marvel started a load of instant hits such as The Avengers, and The Amazing Spider-Man, but will Marvel be changing a lot of things for sure.
Marvel will be starting up with new hits such as Doctor Strange, Black Panther, and The Inhuman's, but will all of these affect the MCU (Marvel Cinematic Universe) in a major way.
In the Captain America Civil War trailer (1st trailer), we saw Bucky mouthing "Steve's DEAD!!!"
Now, of course, we cant jump to conclusions, but that's what it looked like.
So my theory is that Steve will die, and the upcoming Captain Marvel will take his place.
Now, of course, Iron Man might also die as well, but he could be replaced by Iron Fist, and Bucky may just die (which may result in the war)
Now, that clears the Civil War incident, but what other characters are we likely to see.
Well, Black Panther for one because he's in the Civil War, and he is going to have his own solo film in 2018, and Spiderman for the same reason.
We may also see the Agents of S.H.I.E.L.D, and Daredevil just because they are still part of the MCU.
We may also see Luke Cage, Jessica Jones, The Inhuman's, and Defenders because they are also part of the MCU, and Marvel has declared that the Avengers Infinity War will be the biggest MCU event ever.
The Guardians of the Galaxy should also appear, since Thanos appeared in their movie, and it has been proven that Thanos is the villian in this series.
Some new people we might see are the upcoming movies for Marvel such as Doctor Strange.
Also, the people we are almost certain about are Ant-Man just because he is new, and he was an instant hit; Black Widow/Hawkeye because they are also big parts; Scarlet Witch, because she is powerful, do she may not die until the end; and Falcon because he stuck with Captain America.
The people who may die before the Avengers Infinity War starts are most likely Steve Rogers, Tony Stark (maybe), and Rhodes (positive).
Thor may die as well only because the Ragnarok.
Original members who MAY live are Thor, Iron Man, Black Widow, Hawkeye, and Hulk.