Check it out:
The most notable difference is the (slightly) extended look at the movie's Stay Puft-like massive villain, Rowan, who we theorized may be a sort of sentient version of the Ghostbusters logo that's fused with a character who was once human.
Look at that big ugly mug:
It's also worth noting that this trailer reveals it's the reboot's version of Spook Central that Rowan is busting through, suggesting his supposed transformation occurs there.
Oh, and this happens, which is the most terrifying thing anyone can possibly imagine:
Poor, poor Patty.
Ghostbusters hits theaters on July 15.